Djinović

Biochemistry & Biophysics | Structural & Computational Biology

Structural Biology of the Cytoskeleton


Kristina Djinovic-Carugo
Group Leader

kristina.djinovic [AT] univie.ac [DOT] at
Phone: +43-1-4277-52203
Campus Vienna Biocenter 5, 1030 Vienna | Room: 1.606

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Research

Animal movement is mediated by striated muscles, with the sarcomere being the basal contractile unit within single muscle fibers. Sarcomeric actin and myosin form cross-linked and interdigitated filament bundles whose sliding motion generates force. Antiparallel actin filaments from adjacent sacromers are anchored at the Z-disk, which plays a central role as the site organizing the molecular machinery that is required for muscle contraction. The Z-

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