Djinović

Biochemistry & Biophysics | Structural & Computational Biology

Structural Biology of the Cytoskeleton


Kristina Djinovic-Carugo
Group Leader

kristina.djinovic [AT] univie.ac [DOT] at
Phone: +43-1-4277-52203
Campus Vienna Biocenter 5, 1030 Vienna | Room: 1.606

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Research

We investigate the molecular mechanisms underlying the actin-based cytoskeleton of striated muscle. A striking feature of muscle proteins, and particularly of the specialised striated muscle sarcomere compartment Z-disk, is the high frequency of multiple protein-protein interactions. We aim to generate detailed structural information on the protein-protein interaction network in the Z-disk, from its basic components - α-actinin and filamin C - to macromolecular complexes and

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