Intra-cellular Communication between the ER and the Nucleus

Shotaro Otsuka
Group Leader [AT] [DOT] at
Phone: +43-1-4277-61665
Dr. Bohr-Gasse 9, 1030 Vienna | Room: 3.506

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How cells achieve intra-cellular communication is one of the fundamental questions in biology. The endoplasmic reticulum (ER) is the largest membrane-bound organelle in the cell and is the site of the synthesis and turnover of a major fraction of lipids and membrane proteins. The ER is connected to the nucleus by junctions with the outer nuclear membrane. This ER-to-nucleus connectivity is crucial for cells to translate signals to the nucleus for maintaining homeostasis and to