Recent publications 2004-2010
Baravalle, G., Brabec, M., Snyers, L., Blaas, D., and Fuchs, R. (2004). Human rhinovirus type 2-antibody complexes enter and infect cells via Fc-gamma receptor IIB1, J Virol 78, 2729-37.
Dickert, F. L., Hayden, O., Bindeus, R., Mann, K. J., Blaas, D., and Waigmann, E. (2004). Bioimprinted QCM sensors for virus detection-screening of plant sap, Anal Bioanal Chem 378, 1929-34.
Herdy, B., Snyers, L., Reithmayer, M., Hinterdorfer, P., and Blaas, D. (2004). Identification of the human rhinovirus serotype 1A binding site on the murine low-density lipoprotein receptor by using human-mouse receptor chimeras, J Virol 78, 6766-74.
Hewat, E. A., and Blaas, D. (2004). Cryoelectron microscopy analysis of the structural changes associated with human rhinovirus type 14 uncoating, J Virol 78, 2935-42.
Kienberger, F., Zhu, R., Moser, R., Blaas, D., and Hinterdorfer, P. (2004). Monitoring RNA release from human rhinovirus by dynamic force microscopy, J Virol 78, 3203-9.
Kienberger, F., Zhu, R., Moser, R., Rankl, C., Blaas, D., and Hinterdorfer, P. (2004). Dynamic force microscopy for imaging of viruses under physiological conditions, Biol Proced Online 6, 120-128.
Konecsni, T., Kremser, L., Snyers, L., Rankl, C., Kilar, F., Kenndler, E., and Blaas, D. (2004). Twelve receptor molecules attach per viral particle of human rhinovirus serotype 2 via multiple modules, FEBS Lett 568, 99-104.
Kremser, L., Blaas, D., and Kenndler, E. (2004). Capillary electrophoresis of biological particles: viruses, bacteria, and eukaryotic cells, Electrophoresis 25, 2282-91.
Kremser, L., Konecsni, T., Blaas, D., and Kenndler, E. (2004). Fluorescence labeling of human rhinovirus capsid and analysis by capillary electrophoresis, Anal Chem 76, 4175-81.
Kremser, L., Okun, V. M., Nicodemou, A., Blaas, D., and Kenndler, E. (2004). Binding of fluorescent dye to genomic RNA inside intact human rhinovirus after viral capsid penetration investigated by capillary electrophoresis, Anal Chem 76, 882-7.
Kremser, L., Petsch, M., Blaas, D., and Kenndler, E. (2004). Labeling of capsid proteins and genomic RNA of human rhinovirus with two different fluorescent dyes for selective detection by capillary electrophoresis, Anal Chem 76, 7360-5.
Verdaguer, N., Fita, I., Reithmayer, M., Moser, R., and Blaas, D. (2004). X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein, Nat Struct Mol Biol 11, 429-34.
Brabec, M., Schober, D., Wagner, E., Bayer, N., Murphy, R. F., Blaas, D., and Fuchs, R. (2005). Opening of size-selective pores in endosomes during human rhinovirus serotype
Kienberger, F., Rankl, C., Pastushenko, V., Zhu, R., Blaas, D., and Hinterdorfer, P. (2005). Visualization of Single Receptor Molecules Bound to Human Rhinovirus under Physiological Conditions, Structure (Camb) 13, 1247-53.
Moser, R., Snyers, L., Wruss, J., Angulo, J., Peters, H., Peters, T., and Blaas, D. (2005). Neutralization of a common cold virus by concatemers of the third ligand binding module of the VLDL-receptor strongly depends on the number of modules, Virology 338, 259-69.
Nicodemou, A., Petsch, M., Konecsni, T., Kremser, L., Kenndler, E., Casasnovas, J. M., and Blaas, D. (2005). Rhinovirus-stabilizing activity of artificial VLDL-receptor variants defines a new mechanism for virus neutralization by soluble receptors, FEBS Lett. 579: 5507-11
Vlasak, M., Goesler, I., and Blaas, D. (2005). Human rhinovirus type 89 variants use heparan sulfate proteoglycan for cell attachment, J Virol 79, 5963-70.
Vlasak, M., Roivainen, M., Reithmayer, M., Goesler, I., Laine, P., Snyers, L., Hovi, T., and Blaas, D. (2005). The minor receptor group of human rhinovirus (HRV) includes HRV23 and HRV25, but the presence of a lysine in the VP1 HI loop is not sufficient for receptor binding, J Virol 79, 7389-95.
Nizet, S., Wruss, J., Landstetter, N., Snyers, L., and Blaas, D. (2005). A mutation in the first ligand binding repeat of the human very low-density lipoprotein receptor results in high affinity binding of the single V1 module to HRV2, J Virol 79, 14730-6.
Kremser, L., Petsch, M., Blaas, D. & Kenndler, E. (2006). Influence of detergent additives on mobility of native and subviral rhinovirus particles in capillary electrophoresis, Electrophoresis 27, 1112-21.
Hayden, O., Lieberzeit, P.A., Blaas, D., and Dickert, F.L. (2006) Artificial antibodies for bioanlyte detection - Sensing viruses and proteins. Adv. Funct. Mat. 16, 1269 - 1278.
Brabec, M., Blaas, D., and Fuchs., R. (2006) Wortmannin delays transfer of human rhinovirus serotype 2 to late endocytic compartments. Biochem. Biophys. Res. Comm. 348:741-9.
Hewat E.A., and Blaas, D. (2006) Nonneutralizing Human Rhinovirus Serotype 2-Specific Monoclonal Antibody 2G2 Attaches to the Region That Undergoes the Most Dramatic Changes upon Release of the Viral RNA. J. Virol. 80:12398-12401.
Artelsmair, H., Kienberger, F., Tinazli, A., Schlapak, R., Zhu, R., Preiner, J., Wruss, J., Kastner, M., Saucedo-Zeni, N., Hoelzl, M., Rankl, Ch., Baumgartner, W., Howorka, S., Blaas, D., Gruber, H.J., Tampé, R., and Hinterdorfer P. (2008) Atomic force microscopy-based nano-chip for the detection of human pathogenic viruses. Small 4: 847-854. Rankl, C., Kienberger, F., Wildling, L., Wruss, J., Gruber, H.J., Blaas, D. and Hinterdorfer, P. (2008). Multiple receptors involved in human rhinovirus attachment to live cells. Proc Natl. Acad. Sci. USA 105: 17778-17783. Kremser, L., D. Blaas, and E. Kenndler. 2009. Virus analysis using electromigration techniques. Electrophoresis 30:133-140.
Khan, A. G., Pichler, J., Rosemann, A., and Blaas, D. (2007) Human Rhinovirus Type 54 Infection via Heparan Sulfate Is Less Efficient and Strictly Dependent on Low Endosomal pH. J. Virol. 81: 4625-4632.
Kienberger, F., Costa, L. T., Zhu, R., Kada, G., Reithmayer, M., Chtcheglova, L., Rankl, C., Pacheco, A. B., Thalhammer, S., Pastushenko, V., Heckl, W. M., Blaas, D., and Hinterdorfer, P. (2007) Dynamic force microscopy imaging of plasmid DNA and viral RNA. Biomaterials 28: 2403-2411.
Wruss, J., Runzler, D., Steiger, C., Chiba, P., Kohler, G., and Blaas, D. (2007) Attachment of VLDL Receptors to an Icosahedral Virus along the 5-fold Symmetry Axis: Multiple Binding Modes Evidenced by Fluorescence Correlation Spectroscopy. Biochemistry 46, 6331-6339.
Ebner, A., Wildling, L., Kamruzzahan, A.S., Rankl, C., Wruss, J., Hahn, C.D., Holzl, M., Zhu, R., Kienberger, F., Blaas, D., Hinterdorfer, P., and Gruber, H.J. (2007). A new, simple method for linking of antibodies to atomic force microscopy tips. Bioconjugate Chemistry 18:1176-1184.
Kremser, L., Bilek, G., Blaas, D., and Kenndler, E. (2007). Capillary electrophoresis of viruses, subviral particles and virus complexes. J. Sep. Sci. 30:1704-1713.
Brabec-Zaruba, M., U. Berka, D. Blaas, and R. Fuchs. 2007. Induction of autophagy does not affect human rhinovirus type 2 production. J. Virol. 81:10815-10817.
Binder, W. H., R. Sachsenhofer, D. Farnik, and D. Blaas. 2007. Guiding the location of nanoparticles into vesicular structures: a morphological study. Phys Chem Chem Phys 9:6435-6441.
Kolivoska, V., V. U. Weiss, L. Kremser, B. Gas, D. Blaas, and E. Kenndler. 2007. Electrophoresis on a microfluidic chip for analysis of fluorescence-labeled human rhinovirus. Electrophoresis 28:4734-4740.
Weiss, V. U., V. Kolivoska, L. Kremser, B. Gas, D. Blaas, and E. Kenndler. 2007. Virus analysis by electrophoresis on a microfluidic chip. J Chromatogr B Analyt Technol Biomed Life Sci 860:173-179.
Laschober, C., J. Wruss, D. Blaas, W. W. Szymanski, and G. Allmaier. 2008. Gas-Phase Electrophoretic Molecular Mobility Analysis of Size and Stoichiometry of Complexes of a Common Cold Virus with Antibody and Soluble Receptor Molecules. Anal. Chem. 80:2261-2264.
Fuchs, R., and Blaas, D. (2008) Human rhinovirus cell entry and uncoating in “Structure-based Study of Viral Replication” R. Holland Cheng and Tatsuo Miyamura (eds.) World Scientific and Imperial College Press (ISBN 981-270-405-1)
Berka, U., A. Khan, D. Blaas and R. Fuchs (2009). HRV2 Uncoating at the Plasma Membrane is not Affected by a pH Gradient but by the Membrane Potential. J Virol, 83: 3778-3787.
Brabec-Zaruba, M., B. Pfanzagl, D. Blaas and R. Fuchs (2009). Site of Human Rhinovirus RNA Uncoating Revealed by Fluorescent in situ Hybridization. J. Virol. 83: 3770-3777.
Pollheimer, P.D., M. Kastner, A. Ebner, D. Blaas, P. Hinterdorfer, H.J. Gruber and S. Howorka (2009). Receptor Arrays for the Selective and Efficient Capturing of Viral Particles. Bioconjug. Chem. 20:466-475
Wruss J., Pollheimer P.D., Meindl I., Reichel A., Schulze K. Schofberger, W., Piehler, J., Tampé R., Blaas, D. and Gruber, H. (2009) Conformation of Receptor Adopted upon Interaction with Virus Revealed by Site-Specific Fluorescence Quenchers and FRET Analysis. J. Am. Chem. Soc., 131: 5478- 5482
Katsarou, K., Serti, E., Tsitoura, P., Lavdas, A.A., Varaklioti, A., Pickl-Herk, A.M., Blaas, D., Oz-Arslan, D., Zhu, R., Hinterdorfer, P., et al. (2009). Green fluorescent protein - Tagged HCV non-enveloped capsid like particles: Development of a new tool for tracking HCV core uptake. Biochimie 91: 903-915
Jenik, M., R. Schirhagl, C. Schirk, O. Hayden, P. Lieberzeit, D. Blaas, G. Paul, and F. L. Dickert. (2009). Sensing picornaviruses using molecular imprinting techniques on a quartz crystal microbalance. Anal. Chem. 81:5320-6.
Weiss, V. U., G. Bilek, A. Pickl-Herk, D. Blaas, and E. Kenndler. (2009). Mimicking virus attachment to host cells employing liposomes: Analysis by chip electrophoresis. Electrophoresis 30:2123-2128.
Weber, C., A. Pickl-Herk, A. G. Khan, S. Strauss, O. Carugo, and D. Blaas. 2009. Predictive bioinformatic identification of minor receptor group human rhinoviruses. FEBS Lett. 583:2547-2551.
Konecsni, T., Berka, U., Pickl-Herk, A., Bilek, G., Khan, A.G., Gajdzig, L., Fuchs, R., and Blaas, D. (2009). Low pH Triggered Beta-propeller Switch of the Low-Density Lipoprotein Receptor Assists Rhinovirus Infection. J. Virol. 83: 10922-10930
Bilek, G., Weiss, V. U., Pickl-Herk, A., Blaas, D., and Kenndler, E. (2009) Chip electrophoretic characterization of liposomes with biological lipid composition: Coming closer to a model for viral infection. Electrophoresis 30: 4292-4299
Grunwald, C., Schulze, K., Reichel, A., Weiss, V. U., Blaas, D., Piehler, J., Wiesmuller, K. H., and Tampe, R. (2010) In situ assembly of macromolecular complexes triggered by light. Proc. Natl. Acad. Sci. USA 107: 6146-6151
Khan, A. G., Pickl-Herk, A., Gajdzig, L., Marlovits, T., Fuchs, R., and Blaas, D. (2010) Human Rhinovirus 14 Enters Rhabdomyosarcoma Cells Expressing ICAM-1 by a clathrin, caveolin, and flotillin-independent pathway. J. Virol. 84: 3984 - 3892
Kienberger, F., R. Zhu, C. Rankl, H. J. Gruber, D. Blaas, and P. Hinterdorfer. 2010. Atomic force microscopy studies of human rhinovirus topology and molecular forces. Methods Enzymol 475:515-39.
Fuchs, R., and D. Blaas. 2010. Uncoating of human rhinoviruses. Rev Med Virol. (in press)
Edlmayr, J., K. Niespodziana, T. Popow-Kraupp, V. Krzyzanek, M. Focke-Tejkl, D. Blaas, M. Grote, and R. Valenta. 2010. Antibodies induced with recombinant VP1 from Human Rhinovirus exhibit cross-neutralization. Eur Respir J. (in press)