Publication archive 2000 - 2006

Kieslinger, M., Woldman, I., Moriggl, R., Hofmann, J., Marine, J.-C., Ihle, J., Beug, H. and T. Decker.2000. Anti-apoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev.14, 232-244.
 
Decker, T. and P. Kovarik. 2000. Serine Phosphorylation of STATs. Oncogene, 19, 2628-2637.
 
Stoiber, D., Kovarik, P. and T. Decker. 2000. Bacterial signals influence Stat1 activation by IFN- through serine phosphorylation and the synthesis of SOCS3 protein. In: Molecular Mechanisms of Signal Transduction, Johannes L. Bos, editor. NATO Science Series A (Life Sciences), Vol. 316, pp. 219-229.
 
Lafont, V., Decker, T. and D. Cantrell. 2000. Antigen receptor signal transduction: activating and inhibitory antigen receptors regulate STAT1 serine phosphorylation.
Eur. J. Immunol. 30, 1851-1860.
 
Shehata, M., Schwarzmeier, J.D., Nguyen S T, Hilgarth, M., Berger, R., Hubmann, R., Kickmaier, S. and T. Decker. 2000. Reconstitution of endogeneous interferon  by recombinant interferon in hairy cell leukaemia. Cancer Research 60, 5420-5426.
 
Karaghiosoff, M., Neubauer, H., Lassnig, C., Kovarik, P., Schindler, H., Pircher, H., McCoy, B.,Bogdan, C., Decker, T., Brem, G., Pfeffer, K. and M. Müller. 2000. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 13, 549-560.
 
Diefenbach A., Jamieson A.M., Liu S.D., Shastri N., and Raulet D.H. Ligands for the murine NKG2D receptor: expression by tumor cells and activation on NK cells and macrophages. Nature Immunology.  1 (2): 119-125 (2000)
 
Stoiber, D., Stockinger, S. Steinlein, P., Kovarik, J. and T. Decker. 2001. Listeria monocytogenes modulates macrophage cytokine responses through STAT1 serine phosphorylation and the induction of SOCS3. J. Immunol., 166, 466-472.
 
Kovarik, P., Mangold, M., Ramsauer, K., Heidari, H., Steinborn, R., Zotter, A., Levy, D.E., Müller, M. and T. Decker. 2001. Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate serine 727 phosphorylation, differentially affecting specific target gene expression. EMBO J., 20, 91-100.
 
Wong, A.H.-T., Durbin, J.E., Dever, T.E., Decker, T. and A. Koromilas. 2001. Enhanced anti-viral and anti-proliferative properties of STAT1 mutant unable to interact with the IFN-inducible protein kinase PKR. J. Biol. Chem. 276, 13727-13737.
 
Woldman, I., Varinou, L., Ramsauer, K., Klose, B. and T. Decker. 2001. The Stat1 binding motif of the IFN- receptor is sufficient to mediate Stat5 activation and its repression by SOCS3. J. Biol. Chem. 276, 45722-45728.
 
Tanamachi, D.M., Hanke T., Takizawa H., Jamieson A.M., and Raulet D.H. Expression of Natural Killer Receptor Alleles at Different Loci Occurs Independently and Is Regulated by Major Histocompatibility Complex Class I Molecules. J. Exp. Med 193 (3):1-10 (2001).
 
Diefenbach, A., Jensen, E.R., Jamieson, A.M., Raulet, D.H. Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 413: 165-171 (2001).
 
Decker, T., Stockinger, S., Karaghiosoff, M.,  Müller,  M. and P. Kovarik. 2002. Interferons and Stats in innate immunity to microorganisms. J. Clinical Invest. 109, 1271-1277.
 
Ramsauer, K., Sadzak, I., Porras, A., Pilz, A., Nebrada, A.R., Decker, T. and P. Kovarik. 2002. p38MAP kinase enhances Stat1-dependent transcription independently of serine 727. Proc. Natl. Acad. Sci. 99: 12859-12864.
 
Stockinger, S., Materna,T., Stoiber, D., Bayr, L., Steinborn, R. Kolbe, T. Unger, H., Chakraborty, T., Levy, D.E., Müller, M. and T. Decker. 2002. Production of type I interferon sensitizes macrophages to cell death induced by Listeria monocytogenes. J. Immunol 169, 6522-6529.
 
Vance R.E., Jamieson A.M., Cado, D. and Raulet D.H. Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. PNAS 99(2): 868-873 (2002).
 
Jamieson, A.M., Diefenbach, A., McMahon, C.W., Carlyle, J., Xiong, N., and Raulet, D.H. The Role of the NKG2D Immunoreceptor in Immune Cell Activation and Natural Killing. Immunity 17: 19-29 (2002).
McMahon, C.W., Zajac, A.J., Jamieson, A.M., Corral, L., Hammer, G., Ahmed, R., Raulet, D.H. Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8+ T cells The Journal of Immunology 169: 1444-1452 (2002).
 
Diefenbach, A., Tomasello, E., Lucas, M., Jamieson, A.M., Hsia, J.K., Vivier, E., Raulet, D.H. Stimulatory and costimulatory functions of the immunoreceptor NKG2D are determined by selective usage of signaling adaptor molecules. Nature Immunology 3: 1142-1149 (2002).
 
Pilz, A., Ramsauer, K., Heidari, H., Leitges, M., Kovarik, P. and T. Decker. 2003. Phosphorylation of the Stat1 transactivation domain required for the response to type I interferons. EMBO Reports, 4, 368-373.
 
Kharagiosoff, M., Steinborn, R., Kovarik, P., Kriegshäuser, G., Baccarini, M., Donabauer, B., Reichart, U., Kolbe, T., Leanderson, T., Bogdan, C., Levy, D., Decker, T. and M. Müller. 2003. Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Nature Immunol. 4, 471-477.
 
Decker, T., Müller, M. and P. Kovarik. 2003. Regulation of Stats by posttranslational modification. In: Signal tranducers ad activators of transcription (Stats): Activation and biology. Seghal, P.B., Hirano, T. and Levy, D.E., eds. Kluwer Academic.
 
Varinou, L., Ramsauer, K., Karaghiosoff, M., Kolbe, T., Pfeffer, K., Müller, M., and Decker, T. (2003). Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19, 793-802.
 
Junqueira-Kipmis, A.P., Kipnis, A., Jamieson, A.M., Gonzalez Juarrero, M., Diefenbach, A., Raulet, D.H., Turner, J., Orme, I.M. NK cells respond to pulmonary infection with mycobacterium tuberculosis, but play a minimal role in protection. Journal of Immunology Dec 1;171(11):6039-45 (2003).
 
Decker, T. 2004 Sepsis: avoiding its deadly toll. J Clin Invest, 113, 1387-1389.
 
Stockinger, S., Reutterer, B., Schellack, C., Brunner, S., Materna, T., Yamamoto, M., Akira, S., Taniguchi, T., Murray, P.J., Müller, M. and T. Decker. 2004. IRF3-dependent induction of type I interferons by intracellular bacteria is mediated by a Toll-like receptor and Nod2-independent mechanism. J. Immunol, 173 : 7416-7425.
 
Jamieson, A.M., Isnard, P., Dorfman, J.R., Coles, M.C., and Raulet, D.H. Turnover and proliferation of natural killer cells in steady state and lymphopenic conditions. Journal of Immunology Jan.15 ; 172:864-870 (2004).
 
Carlyle, J.R., Jamieson A.M., Gasser, S., Clingan, C.S., Arase, H., and Raulet D.H. Missing self recognition of Ocil/Clr-B by inhibitory NKR-P1 Orphan Natural Killer Cell receptors. PNAS Mar 9;101(10):3527-32 (2004).
 
Street, S.E.A., Hayakawa, Y., Zhan, Y., Lew, A. M., MacGregor, D., Jamieson, A.M., Diefenbach, A., Yagita, H., Godfrey, D.I., and Smyth, M.J. Innate immune surveillance of spontaneous B cell lymphomas by NK cells and  T cells. Journal of Experimental Medicine Mar 15; 199(6):879-84 (2004).
 
Decker, T., Müller, M. and S. Stockinger. 2005. The Yin and Yang of type I IFN activity in bacterial infection. Nature Rev. Immunol. 5, 675-687.
 
Fernandez, N.C., Vance, R.E., Jamieson, A.M., Lemieux, S., and Raulet, D.H. A subset of NK cells achieve self-tolerance without expressing inhibitory receptors specific for self MHC molecules. Blood Jun 1;105(11):4416-23 (2005).
 
Soulat, D., Bauch, A., Stockinger, S., Superti-Furga, G. and T. Decker. 2006.  Cytoplasmic Listeria monocytogenes stimulates IFN- synthesis without requiring the adapter protein MAVS.  FEBS Letters, 580 : 2341-2346.
 
Zupkovitz G, Tischler J, Posch M, Sadzak I, Ramsauer K, Egger G, Grausenburger R, Schweifer N, Chiocca S, Decker T, Seiser C. 2006. Negative and positive regulation of gene expression by mouse histone deacetylase 1. Mol. Cell. Biol., 26 : 7913-7928.