Archive

Reviews

  • RAJKOWITSCH L., CHEN D., STAMPFL S., SEMRAD K., WALDSICH C., MAYER O., JANTSCH M.F., KONRAT R., BLÄSI U., SCHROEDER R. (2007) RNA Chaperones, RNA Annealers and RNA Helicases. RNA Biol. 4:118-130 | FREE PDF | PubMed | associated RNA chaperone activity website |  
  • CHARPENTIER E., SCHROEDER R. (2007) RNA techniques for bacteria. Curr Opin Microbiol 10: 254-256. | PubMed |
  • RAJKOWITSCH L., SEMRAD K., MAYER O., SCHROEDER R. (2005) Assays for the RNA chaperone activity of proteins. Biochem Soc Trans 33: 450-456. | PubMed |
  • WINDBICHLER N., SCHROEDER R. (2004) Double duty. Nat Struct Mol Biol 11: 910-911. | PubMed |
  • SCHROEDER R., BARTA A., SEMRAD K. (2004) Strategies for RNA folding and assembly. Nat Rev Mol Cell Biol 5: 908-919. | PubMed |
  • PIGANEAU N., SCHROEDER R. (2003) Aptamer structures: a preview into regulatory pathways? Chem Biol 10: 103-104. | PubMed |
  • MAYER O., WALDSICH C., GROSSBERGER R., SCHROEDER R. (2002) Folding of the td pre-RNA with the help of the RNA chaperone StpA. Biochem Soc Trans 30: 1175-1180. | PubMed |
  • SCHROEDER R., GROSSBERGER R., PICHLER A., WALDSICH C. (2002) RNA folding in vivo. Curr Opin Struct Biol 12: 296-300. | PubMed |
  • SCHROEDER R., WALDSICH C., WANK H. (2000) Modulation of RNA function by aminoglycoside antibiotics. EMBO J 19: 1-9. | PubMed | FREE PDF |
  • WALLIS M. G., SCHROEDER R. (1997) The binding of antibiotics to RNA. Prog Biophys Mol Biol 67: 141-154. | PubMed |
  • SCHROEDER R. (1994) Translation. Dissecting RNA function. Nature 370: 597-598. | PubMed |
  • SCHROEDER R., STREICHER B., WANK H. (1993) Splice-site selection and decoding: are they related? Science 260: 1443-1444. | PubMed |
  • VON AHSEN U., SCHROEDER R. (1993) RNA as a catalyst: natural and designed ribozymes. Bioessays 15: 299-307. | PubMed |

Research articles

  • TAFER H.*, AMERES S.L.*, OBERNOSTERER G.*, GEBESHUBER C.A., SCHROEDER R., MARTINEZ J., HOFACKER I.L. (2008) The impact of target site accessibility on the design of effective siRNAs. Nature Biotechnol. Epub. *equal contribution | PubMed | FREE PDF | 
  • WINDBICHLER N., VON PELCHRZIM F., MAYER O., CSASZAR E., SCHROEDER R. (2008) Isolation of small RNA-binding proteins from E. coli: Evidence for frequent interaction of RNAs with RNA polymerase. RNA Biol. 5 | FREE PDF |
  • VECEREK B.*, RAJKOWITSCH L.*, SONNLEITNER E., SCHROEDER R., BLÄSI U. (2007) The C-terminal domain of Escherichia coli Hfq is required for regulation. Nucleic Acids Res *equal contribution | PubMed | FREE PDF |
  •  WEIGAND J.E., SANCHEZ M., GUNNESCH E.B., ZEIHER S., SCHROEDER R., SUESS. B. (2007) Screening for engineered neomycin riboswitches that control translation initiation. RNA | Epub |
  • RAJKOWITSCH L., SCHROEDER, R. (2007a) Dissecting RNA chaperone activity. RNA 13: 2053-2060. | PubMed | FREE PDF |
  • AMERES S. L., MARTINEZ J., SCHROEDER R. (2007a) Molecular Basis for Target RNA Recognition and Cleavage by Human RISC. Cell 130: 101-112. | PubMed |
  • AMERES S. L., SHCHERBAKOV D., NIKONOVA E., PIENDL W., SCHROEDER R., SEMRAD K. (2007b) RNA chaperone activity of L1 ribosomal proteins: phylogenetic conservation and splicing inhibition. Nucleic Acids Res 35: 3752-3763. | PubMed | FREE PDF |
  • STAMPFL S., LEMPRADL A., KOEHLER G., SCHROEDER R. (2007) Monovalent Ion Dependence of Neomycin B Binding to an RNA Aptamer Characterized by Spectroscopic Methods. Chembiochem 8: 1137-1145. | PubMed |
  • PANZITT K., TSCHERNATSCH M. M., GUELLY C., MOUSTAFA T., STRADNER M., STROHMAIER H. M., BUCK C. R., DENK H., SCHROEDER R., TRAUNER M., ZATLOUKAL K. (2007) Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. Gastroenterology 132: 330-342. | PubMed |
  • MAYER O., RAJKOWITSCH L., LORENZ C., KONRAT R., SCHROEDER R. (2007) RNA chaperone activity and RNA-binding properties of the E. coli protein StpA. Nucleic Acids Res 35:1257-1269. | PubMed | FREE PDF |
  • LORENZ C., PIGANEAU N., SCHROEDER R. (2006) Stabilities of HIV-1 DIS type RNA loop-loop interactions in vitro and in vivo. Nucleic Acids Res 34: 334-342. | PubMed | FREE PDF |
  • PIGANEAU N., SCHAUER U. E., SCHROEDER R. (2006) A yeast RNA-hybrid system for the detection of RNA-RNA interactions in vivo. RNA 12: 177-184. | PubMed | FREE PDF |
  • BELISOVA A., SEMRAD K., MAYER O., KOCIAN G., WAIGMANN E., SCHROEDER R., STEINER G. (2005) RNA chaperone activity of protein components of human Ro RNPs. RNA 11: 1084-1094. | PubMed | FREE PDF |
  • GROSSBERGER R., MAYER O., WALDSICH C., SEMRAD K., URSCHITZ S., SCHROEDER R. (2005) Influence of RNA structural stability on the RNA chaperone activity of the Escherichia coli protein StpA. Nucleic Acids Res 33: 2280-2289. | PubMed | FREE PDF |
  • SEMRAD K., GREEN R., SCHROEDER R. (2004) RNA chaperone activity of large ribosomal subunit proteins from Escherichia coli. RNA 10: 1855-1860. | PubMed | FREE PDF |
  • WEIXLBAUMER A., WERNER A., FLAMM C., WESTHOF E., SCHROEDER R. (2004) Determination of thermodynamic parameters for HIV DIS type loop-loop kissing complexes. Nucleic Acids Res 32: 5126-5133. | PubMed | FREE PDF |
  • SUESS B., HANSON S., BERENS C., FINK B., SCHROEDER R., HILLEN W. (2003) Conditional gene expression by controlling translation with tetracycline-binding aptamers. Nucleic Acids Res 31: 1853-1858. | PubMed | FREE PDF |
  • WINDBICHLER N., WERNER M., SCHROEDER R. (2003) Kissing complex-mediated dimerisation of HIV-1 RNA: coupling extended duplex formation to ribozyme cleavage. Nucleic Acids Res 31: 6419-6427. | PubMed | FREE PDF |
  • PICHLER A., SCHROEDER R. (2002) Folding problems of the 5' splice site containing the P1 stem of the group I thymidylate synthase intron: substrate binding inhibition in vitro and mis-splicing in vivo. J Biol Chem 277: 17987-17993. | PubMed | FREE PDF |
  • WALDSICH C., GROSSBERGER R., SCHROEDER R. (2002a) RNA chaperone StpA loosens interactions of the tertiary structure in the td group I intron in vivo. Genes Dev 16: 2300-2312. | PubMed | FREE PDF |
  • WALDSICH C., MASQUIDA B., WESTHOF E., SCHROEDER R. (2002b) Monitoring intermediate folding states of the td group I intron in vivo. EMBO J 21: 5281-5291. | PubMed | FREE PDF |
  • BERENS C., THAIN A., SCHROEDER R. (2001) A tetracycline-binding RNA aptamer. Bioorg Med Chem 9: 2549-2556. | PubMed |
  • WITTBERGER D., BERENS C., HAMMANN C., WESTHOF E., SCHROEDER R. (2000) Evaluation of uranyl photocleavage as a probe to monitor ion binding and flexibility in RNAs. J Mol Biol 300: 339-352. | PubMed |
  • BACHLER M., SCHROEDER R., VON AHSEN U. (1999) StreptoTag: a novel method for the isolation of RNA-binding proteins. RNA 5: 1509-1516. | PubMed | FREE PDF |
  • BRION P., MICHEL F., SCHROEDER R., WESTHOF E. (1999a) Analysis of the cooperative thermal unfolding of the td intron of bacteriophage T4. Nucleic Acids Res 27: 2494-2502. | PubMed | FREE PDF |
  • BRION P., SCHROEDER R., MICHEL F., WESTHOF E. (1999b) Influence of specific mutations on the thermal stability of the td group I intron in vitro and on its splicing efficiency in vivo: a comparative study. RNA 5: 947-958. | PubMed | FREE PDF |
  • CLODI E., SEMRAD K., SCHROEDER R. (1999) Assaying RNA chaperone activity in vivo using a novel RNA folding trap. EMBO J 18: 3776-3782. | PubMed | FREE PDF |
  • WANK H., CLODI E., WALLIS M. G., SCHROEDER R. (1999) The antibiotic viomycin as a model peptide for the origin of the co-evolution of RNA and proteins. Orig Life Evol Biosph 29: 391-404. | PubMed |
  • BERENS C., STREICHER B., SCHROEDER R., HILLEN W. (1998) Visualizing metal-ion-binding sites in group I introns by iron(II)-mediated Fenton reactions. Chem Biol 5: 163-175. | PubMed |
  • HOCH I., BERENS C., WESTHOF E., SCHROEDER R. (1998) Antibiotic inhibition of RNA catalysis: neomycin B binds to the catalytic core of the td group I intron displacing essential metal ions. J Mol Biol 282: 557-569. | PubMed |
  • SEMRAD K., SCHROEDER R. (1998) A ribosomal function is necessary for efficient splicing of the T4 phage thymidylate synthase intron in vivo. Genes Dev 12: 1327-1337. | PubMed |
  • WALDSICH C., SEMRAD K., SCHROEDER R. (1998) Neomycin B inhibits splicing of the td intron indirectly by interfering with translation and enhances missplicing in vivo. RNA 4: 1653-1663. | PubMed | FREE PDF |
  • WALLACE S. T., SCHROEDER R. (1998) In vitro selection and characterization of streptomycin-binding RNAs: recognition discrimination between antibiotics. RNA 4: 112-123. | PubMed | FREE PDF |
  • VON AHSEN U., GREEN R., SCHROEDER R., NOLLER H. F. (1997) Identification of 2'-hydroxyl groups required for interaction of a tRNA anticodon stem-loop region with the ribosome. RNA 3: 49-56. | PubMed | FREE PDF |
  • WALLIS M. G., STREICHER B., WANK H., VON AHSEN U., CLODI E., WALLACE S. T., FAMULOK M., SCHROEDER R. (1997) In vitro selection of a viomycin-binding RNA pseudoknot. Chem Biol 4: 357-366. | PubMed |
  • ROGERS J., CHANG A. H., VON AHSEN U., SCHROEDER R., DAVIES J. (1996) Inhibition of the self-cleavage reaction of the human hepatitis delta virus ribozyme by antibiotics. J Mol Biol 259: 916-925. | PubMed |
  • STREICHER B., WESTHOF E., SCHROEDER R. (1996) The environment of two metal ions surrounding the splice site of a group I intron. EMBO J 15: 2556-2564. | PubMed | FREE PDF |
  • WANK H., SCHROEDER R. (1996) Antibiotic-induced oligomerisation of group I intron RNA. J Mol Biol 258: 53-61. | PubMed |
  • WALLIS M. G., VON AHSEN U., SCHROEDER R., FAMULOK M. (1995) A novel RNA motif for neomycin recognition. Chem Biol 2: 543-552. | PubMed |
  • WANK H., ROGERS J., DAVIES J., SCHROEDER R. (1994) Peptide antibiotics of the tuberactinomycin family as inhibitors of group I intron RNA splicing. J Mol Biol 236: 1001-1010. | PubMed |
  • STREICHER B., VON AHSEN U., SCHROEDER R. (1993) Lead cleavage sites in the core structure of group I intron-RNA. Nucleic Acids Res 21: 311-317. | PubMed | FREE PDF |
  • VON AHSEN U., DAVIES J., SCHROEDER R. (1992) Non-competitive inhibition of group I intron RNA self-splicing by aminoglycoside antibiotics. J Mol Biol 226: 935-941. | PubMed |
  • SCHROEDER R., VON AHSEN U., BELFORT M. (1991) Effects of mutations of the bulged nucleotide in the conserved P7 pairing element of the phage T4 td intron on ribozyme function. Biochemistry 30: 3295-3303. | PubMed |
  • VON AHSEN U., DAVIES J., SCHROEDER R. (1991) Antibiotic inhibition of group I ribozyme function. Nature 353: 368-370. | PubMed |
  • VON AHSEN U., SCHROEDER R. (1991) Streptomycin inhibits splicing of group I introns by competition with the guanosine substrate. Nucleic Acids Res 19: 2261-2265. | PubMed |
  • VON AHSEN U., SCHROEDER R. (1990) Streptomycin and self-splicing. Nature 346: 801. | PubMed | FREE PDF |
  • EHRENMAN K., SCHROEDER R., CHANDRY P. S., HALL D. H., BELFORT M. (1989) Sequence specificity of the P6 pairing for splicing of the group I td intron of phage T4. Nucleic Acids Res 17: 9147-9163. | PubMed | FREE PDF |

Method articles

  • RAJKOWITSCH L., SCHROEDER, R. (2007) Coupling RNA annealing and strand displacement: A FRET-based microplate reader assay for RNA chaperone activity. BioTechniques 43: 304-310. | PubMed |
  • LORENZ C., VON PELCHRZIM F. SCHROEDER R. Genomic SELEX for the identification of functional RNAs independent of their expression level. Nat Protocols 1: 2204-2212. | PubMed |
  • PRENNINGER S., SCHROEDER R. SEMRAD K. (2006) Assaying RNA chaperone activity in vivo using a ribozyme folding trap. Nat Protocols 1: 1274-1278. | PubMed |
  • DANGERFIELD J. A., WINDBICHLER N., SALMONS B., GUNZBURG W. H., SCHRODER R. (2006) Enhancement of the StreptoTag method for isolation of endogenously expressed proteins with complex RNA binding targets. Electrophoresis 27: 1874-1877. | PubMed |
  • WINDBICHLER N. & SCHROEDER R. (2006) Isolation of specific RNA-binding proteins using the streptomycin-binding RNA aptamer. Nat Protocols 1: 637-640. | PubMed |
  • PIGANEAU N. & SCHROEDER R. (2006) Identification and detection of RNA-RNA interactions using the yeast RNA hybrid system. Nat Protocols 1: 689-694. | PubMed |
  • WALLACE S. T., SCHROEDER R. (2000) In vitro selection and characterization of RNAs with high affinity to antibiotics. Methods Enzymol 318: 214-229. | PubMed |

Book chapters

  • STAMPFL S., RAJKOWITSCH L., SEMRAD K., SCHROEDER R. (2008) Mode of Action of Proteins with RNA Chaperone Activity. In "Protein-Nucleic Acid Interactions", Eds. Phoebe A. Rice & Carl C. Correll, RSC Biomolecular Sciences, Cambridge, UK | Buy this book at Amazon.com |
  • LORENZ, C. & SCHROEDER, R. (2006) Aptamers to Anibiotics. In "The Aptamer Handbook", Ed.: Sven Kussmann, WILEY-VCH GmbH & Co. KgaA, Weinheim, pp 116-130 | Buy this book at Amazon.com |
  • HOCH, I. and SCHROEDER, R. (2001): Inhibition of group I intron activity by antibiotics. In "RNA-binding antibiotics", R. Schroeder, and M.G. Wallis eds. Landes Biosciences, Georgetown USA, pp 24-34
  • PICHLER, A., BERENS, C. and SCHROEDER, R. (2000) Localization of Metal Ion Binding Sites in Group I Intron RNA in "Ribozyme, Biochemistry and Biotechnology" G. Krupp & R.K. Gaur, eds. Eaton Publishing, Natick USA, pp 7-25
  • SCHROEDER, R. and von AHSEN, U. (1996) Interaction of aminoglycoside antibiotics with RNA. In "Nucleic Acids & Molecular Biology vol 10", F. Eckstein, D.M. Lilley, eds. Springer Verlag, Berlin, pp 53-74
  • SCHROEDER, R. (1996) Activities of group I introns. In: "Group I introns and ribosomal RNA" R. Green and R. Schroeder, eds. Landes Bioscience Publishers, Georgetown USA, pp 83-101
  • WANK, H. and SCHROEDER, R. (1996) Antibiotics that interfere with RNA/RNA interactions. In: "Group I introns and ribosomal RNA" R. Green and R. Schroeder, eds. Landes Bioscience Publishers, Georgetown USA, pp 129-151
  • DAVIES, J., von AHSEN, U., and SCHROEDER, R. (1993) Antibiotics and the RNA World; A role for low molecular weight effectors in biochemical evolution? In:"The RNA World" J.F. Atkins and R.F. Gesteland, eds. Cold Spring Harbour, pp. 185-204
  • DAVIES, J., von AHSEN, U., WANK, H. and SCHROEDER, R. (1992) Evolution of secondary metabolite production: potential roles for antibiotics as prebiotic effectors of catalytic RNA reactions. In "Secondary metabolites: their function and evolution" CIBA Foundation Symposium, vol 171, pp. 24-44


Book editorials

  • "RNA-binding antibiotics" by R. Schroeder & M.G. Wallis (Eds.) Molecular Biology Intelligence Unit, R.G. Landes Company, Georgetown USA , 2001.  | Buy this book at Amazon.com |
  • "Self-splicing Group I Introns And Ribosomal RNAs." by R. Green & R. Schroeder (Eds.). Molecular Biology Intelligence Unit, R.G. Landes Company, Georgetown, USA , 1996  | Buy this book at Amazon.com |

 

Archive content
Reviews
Research articles
Method articles
Book chapters
Book editorials

 

Page last updated
in April 2008 

Downloads