GROUP ZAGROVIC | Biochemistry & Biophysics, Structural & Computational Biology

Computational Biophysics of Macromolecules

Bojan Zagrovic
Group Leader

Phone: +43-1-4277-52271
Dr. Bohr-Gasse 9 (VBC 5), 1030 Vienna | Room: 1.601


Biological function on the molecular level is directly related to the 3-dimensional structure of biomolecules, their dynamics and finally their interactions, both with the environment as well as with other biomolecules. Conceptually, the research interests of our laboratory revolve around exploring different faces of this fundamental principle through the use of computational and theoretical methods in close collaboration with experimentalists.


While experimental approaches are making breathtaking steps forward, currently the only way to probe biomolecular structure and dynamics on a...


Alexander Beribisky| Anita de Ruiter| Markus Fleck| Matea Hajnic| Mario Hlevnjak| Gerald Platzer| Anton Polyansky|

Selected Publications

Hlevnjak, Mario; Polyansky, Anton A; Zagrovic, Bojan (2012). Sequence signatures of direct complementarity between mRNAs and cognate proteins on multiple levels. NUCLEIC ACIDS RES;40(18):8874-82. PMID: 22844092

Polyansky AA, Hlevnjak M & Zagrovic B. (2013). Analogue encoding of physicochemical properties of proteins in their cognate messenger RNAs. Nature "Communications"(4):2784. PMID: 24253588

Petrov D, Margreitter C, Grandits M, Oostenbrink C, Zagrovic B (2013). A systematic framework for molecular dynamics simulations of protein post-translational modifications PLOS COMPUT BIOL;9(7):e1003154. PMID: 23874192

Collaboration & Funding

ERC Starting Grant 2011

ERC Starting Grant 2011

Awardee of a "Starting Independent Researcher Grant" from the European Research Council ERC

START Prize 2010, Austrian Science Fund (FWF)

START Prize 2010, Austrian Science Fund (FWF)

Project title: "Specific and global aspects of protein interactions"