Publications since 2006

Kovarik, Pavel; Ebner, Florian; Sedlyarov, Vitaly (2017). Posttranscriptional regulation of cytokine expression. Cytokine.;89:21-26. PMID: 26586165
Lang, Michaela; Berry, David; Passecker, Katharina; Mesteri, Ildiko; Bhuju, Sabin; Ebner, Florian; Sedlyarov, Vitaly; Evstatiev, Rayko; Dammann, Kyle; Loy, Alexander; Kuzyk, Orest; Kovarik, Pavel; Khare, Vineeta; Beibel, Martin; Roma, Guglielmo; Meisner-Kober, Nicole; Gasche, Christoph (2017). HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis. CANCER RES;9(77). PMID: 28428272
Fallmann, Jörg; Sedlyarov, Vitaly; Tanzer, Andrea; Kovarik, Pavel; Hofacker, Ivo L (2016). AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements. NUCLEIC ACIDS RES;4(44):D90-5. PMID: 26602692
Castiglia, Virginia; Piersigilli, Alessandra; Ebner, Florian; Janos, Marton; Goldmann, Oliver; Damböck, Ursula; Kröger, Andrea; Weiss, Sigfried; Knapp, Sylvia; Jamieson, Amanda M; Kirschning, Carsten; Kalinke, Ulrich; Strobl, Birgit; Müller, Mathias; Stoiber, Dagmar; Lienenklaus, Stefan; Kovarik, Pavel (2016). Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. Cell Host Microbe;19(3):375-87. PMID: 26962946
Sedlyarov, Vitaly; Fallmann, Jörg; Ebner, Florian; Huemer, Jakob; Sneezum, Lucy; Ivin, Masa; Kreiner, Kristina; Tanzer, Andrea; Vogl, Claus; Hofacker, Ivo; Kovarik, Pavel (2016). Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution. MOL SYST BIOL;12(5):868. PMID: 27178967
Gamradt, Pia; Xu, Yun; Gratz, Nina; Duncan, Kellyanne; Kobzik, Lester; Högler, Sandra; Kovarik, Pavel; Decker, Thomas; Jamieson, Amanda M (2016). The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes. PLOS PATHOG;12(12):e1006032. PMID: 27973535
Kovarik, Pavel; Castiglia, Virginia; Ivin, Masa; Ebner, Florian (2016). Type I Interferons in Bacterial Infections: A Balancing Act. Frontiers in immunology;7:652. PMID: 28082986
Wiesauer, Ivana; Gaumannmüller, Clemens; Steinparzer, Iris; Strobl, Birgit; Kovarik, Pavel (2015). Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription. MOL CELL BIOL;35(4):716-27.. PMID: 25512607
Fieber, Christina; Janos, Marton; Koestler, Tina; Gratz, Nina; Li, Xiao-Dong; Castiglia, Virginia; Aberle, Marion; Sauert, Martina; Wegner, Mareike; Alexopoulou, Lena; Kirschning, Carsten J; Chen, Zhijian J; von Haeseler, Arndt; Kovarik, Pavel (2015). Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2. PLOS ONE;10(3):e0119727. PMID: 25756897
Kratochvill, Franz; Gratz, Nina; Qualls, Joseph E; Van De Velde, Lee-Ann; Chi, Hongbo; Kovarik, Pavel; Murray, Peter J (2015). Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. CANCER RES;75(15):3054-64. PMID: 26183929
Dinis, Márcia; Plainvert, Céline; Kovarik, Pavel; Longo, Magalie; Fouet, Agnès; Poyart, Claire (2014). The Innate Immune Response Elicited by Group A Streptococcus Is Highly Variable among Clinical Isolates and Correlates with the emm Type. PLOS ONE;9(7):e101464. PMID: 24991887
Fieber, Christina; Kovarik, Pavel (2014). Responses of innate immune cells to group A Streptococcus. Frontiers in cellular and infection microbiology;4:140. PMID: 25325020
Kovarik, Pavel; Castiglia, Virginia; Janos, Marton (2014). Type I Interferons in Immune Defense Against Streptococci. Bacterial Activation of Type I Interferons:43-59.
Bancerek, Joanna; Poss, Zachary C; Steinparzer, Iris; Sedlyarov, Vitaly; Pfaffenwimmer, Thaddäus; Mikulic, Ivana; Dölken, Lars; Strobl, Birgit; Müller, Mathias; Taatjes, Dylan J; Kovarik, Pavel (2013). CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response. IMMUNITY:250-62. PMID: 23352233
Gruber AR; Fallmann J; Kratochvill F; Kovarik P; Hofacker I. (2011). AREsite: a database for the comprehensive investigation of AU-rich elements NUCLEIC ACIDS RES. PMID: 21071424
Roetzer A; Klopf E; Gratz N; Marcet-Houben M; Hiller E; Rupp S; Gabaldón T; Kovarik P; Schüller C. (2011). Regulation of Candida glabrata oxidative stress resistance is adapted to host environment. FEBS Lett;585(2):319-27. PMID: 21156173
Gratz, Nina; Hartweger, Harald; Matt, Ulrich; Kratochvill, Franz; Janos, Marton; Sigel, Stefanie; Drobits, Barbara; Li, Xiao-Dong; Knapp, Sylvia; Kovarik, Pavel (2011). Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLOS PATHOG;7(5):e1001345. PMID: 21625574
Kratochvill, Franz; Machacek, Christian; Vogl, Claus; Ebner, Florian; Sedlyarov, Vitaly; Gruber, Andreas R; Hartweger, Harald; Vielnascher, Raimund; Karaghiosoff, Marina; Rülicke, Thomas; Müller, Mathias; Hofacker, Ivo; Lang, Roland; Kovarik, Pavel (2011). Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. MOL SYST BIOL;7:560. PMID: 22186734
Roetzer, Andreas; Gratz, Nina; Kovarik, Pavel; Schüller, Christoph (2010). Autophagy supports Candida glabrata survival during phagocytosis. CELL MICROBIOL. PMID: 19811500
Vogl, Claus; Flatt, Thomas; Fuhrmann, Bernd; Hofmann, Elisabeth; Wallner, Barbara; Stiefvater, Rita; Kovarik, Pavel; Strobl, Birgit; Müller, Mathias (2010). Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes. BMC GENOMICS. PMID: 20338026