Publications since 2006

Agustinho, Daniel Paiva; de Oliveira, Marco Antônio; Tavares, Aldo Henrique; Derengowski, Lorena; Stolz, Valentina; Guilhelmelli, Fernanda; Mortari, Márcia Renata; Kuchler, Karl; Silva-Pereira, Ildinete (2017). Dectin-1 is required for miR155 upregulation in murine macrophages in response to Candida albicans. Virulence.;8(1):41-52. PMID: 27294852
Nogueira, Filomena; Istel, Fabian; Pereira, Leonel; Tscherner, Michael; Kuchler, Karl (2017). Immunological Identification of Fungal Species. Meth Mol Biol;1508:339-359. PMID: 27837515
Jenull, Sabrina; Tscherner, Michael; Gulati, Megha; Nobile, Clarissa J; Chauhan, Neeraj; Kuchler, Karl (2017). The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals. Scientific reports.;7(1):8308. PMID: 28814742
Montanari, Floriane; Pinto, Marta; Khunweeraphong, Narakorn; Wlcek, Katrin; Sohail, M Imran; Noeske, Tobias; Boyer, Scott; Chiba, Peter; Stieger, Bruno; Kuchler, Karl; Ecker, Gerhard F (2016). Flagging drugs that inhibit the bile salt export pump. Molecular pharmaceutics.;13(1):163-71. PMID: 26642869
Schwarz, Theresa; Montanari, Floriane; Cseke, Anna; Wlcek, Katrin; Visvader, Lene; Palme, Sarah; Chiba, Peter; Kuchler, Karl; Urban, Ernst; Ecker, Gerhard F (2016). Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P-Glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). ChemMedChem.;11(12):1380-94. PMID: 26970257
Wirnsberger, Gerald; Zwolanek, Florian; Asaoka, Tomoko; Kozieradzki, Ivona; Tortola, Luigi; Wimmer, Reiner A; Kavirayani, Anoop; Fresser, Friedrich; Baier, Gottfried; Langdon, Wallace Y; Ikeda, Fumiyo; Kuchler, Karl; Penninger, Josef M (2016). Inhibition of CBLB protects from lethal Candida albicans sepsis. Nature medicine.;22(8):915-23. PMID: 27428901
Xie J, Jenull S, Tscherner M, Kuchler K (2016). The paralogous histone deacetylases Rpd3 and Rpd31 play opposing roles in regulating the white-opaque switch in the fungal pathogen Candida albicans. mBio:e01807-16. PMID: 27935838
Kuchler, Karl; Jenull, Sabrina; Shivarathri, Raju; Chauhan, Neeraj (2016). Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs? PLOS PATHOG;12(11):e1005938. PMID: 27832212
Tscherner, Michael; Zwolanek, Florian; Jenull, Sabrina; Sedlazeck, Fritz J; Petryshyn, Andriy; Frohner, Ingrid E; Mavrianos, John; Chauhan, Neeraj; von Haeseler, Arndt; Kuchler, Karl (2015). The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways. PLOS PATHOG;11(10):e1005218. PMID: 26473952
Mota, Sandra; Alves, Rosana; Carneiro, Catarina; Silva, Sónia; Brown, Alistair J; Istel, Fabian; Kuchler, Karl; Sampaio, Paula; Casal, Margarida; Henriques, Mariana; Paiva, Sandra (2015). Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate. Front Microbiol;6:919. PMID: 26388859
Brunke, Sascha; Quintin, Jessica; Kasper, Lydia; Jacobsen, Ilse D; Richter, Martin E; Hiller, Ekkehard; Schwarzmüller, Tobias; d'Enfert, Christophe; Kuchler, Karl; Rupp, Steffen; Hube, Bernhard; Ferrandon, Dominique (2015). Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts. Disease models & mechanisms.;8(5):473-86. PMID: 25786415
Zwolanek, Florian; Riedelberger, Michael; Stolz, Valentina; Jenull, Sabrina; Istel, Fabian; Köprülü, Afitap Derya; Ellmeier, Wilfried; Kuchler, Karl (2014). The Non-receptor Tyrosine Kinase Tec Controls Assembly and Activity of the Noncanonical Caspase-8 Inflammasome. PLOS PATHOG;10(12):e1004525. PMID: 25474208
Wartenberg, Anja; Linde, Jörg; Martin, Ronny; Schreiner, Maria; Horn, Fabian; Jacobsen, Ilse D; Jenull, Sabrina; Wolf, Thomas; Kuchler, Karl; Guthke, Reinhard; Kurzai, Oliver; Forche, Anja; d'Enfert, Christophe; Brunke, Sascha; Hube, Bernhard (2014). Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant. PLOS GENET;10(12):e1004824. PMID: 25474009
Wirnsberger, Gerald; Zwolanek, Florian; Stadlmann, Johannes; Tortola, Luigi; Liu, Shang Wan; Perlot, Thomas; Järvinen, Päivi; Dürnberger, Gerhard; Kozieradzki, Ivona; Sarao, Renu; De Martino, Alba; Boztug, Kaan; Mechtler, Karl; Kuchler, Karl; Klein, Christoph; Elling, Ulrich; Penninger, Josef M (2014). Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. NAT GENET;46(9):1028-33. PMID: 25129145
Schwarzmüller, Tobias; Ma, Biao; Hiller, Ekkehard; Istel, Fabian; Tscherner, Michael; Brunke, Sascha; Ames, Lauren; Firon, Arnaud; Green, Brian; Cabral, Vitor; Marcet-Houben, Marina; Jacobsen, Ilse D; Quintin, Jessica; Seider, Katja; Frohner, Ingrid; Glaser, Walter; Jungwirth, Helmut; Bachellier-Bassi, Sophie; Chauvel, Murielle; Zeidler, Ute; Ferrandon, Dominique; Gabaldón, Toni; Hube, Bernhard; d'Enfert, Christophe; Rupp, Steffen; Cormack, Brendan; Haynes, Ken; Kuchler, Karl (2014). Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes. PLOS PATHOG;10(6):e1004211. PMID: 24945925
Nobile, Clarissa J; Fox, Emily P; Hartooni, Nairi; Mitchell, Kaitlin F; Hnisz, Denes; Andes, David R; Kuchler, Karl; Johnson, Alexander D (2014). A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans. mBio;5(3):e01201-14. PMID: 24917598
Kasper, Lydia; Seider, Katja; Gerwien, Franziska; Allert, Stefanie; Brunke, Sascha; Schwarzmüller, Tobias; Ames, Lauren; Zubiria-Barrera, Cristina; Mansour, Michael K; Becken, Ulrike; Barz, Dagmar; Vyas, Jatin M; Reiling, Norbert; Haas, Albert; Haynes, Ken; Kuchler, Karl; Hube, Bernhard (2014). Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages. PLOS ONE;9(5):e96015. PMID: 24789333
Lackner, M; Tscherner, M; Schaller, M; Kuchler, K; Mair, C; Sartori, B; Istel, F; Arendrup, M C; Lass-Flörl, C (2014). Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment. ANTIMICROB AGENTS CH;58(7):3626-35. PMID: 24733467
Seider, Katja; Gerwien, Franziska; Kasper, Lydia; Allert, Stefanie; Brunke, Sascha; Jablonowski, Nadja; Schwarzmüller, Tobias; Barz, Dagmar; Rupp, Steffen; Kuchler, Karl; Hube, Bernhard (2014). Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. EUKARYOT CELL;13(1):170-83. PMID: 24363366
Köprülü, Afitap Derya; Kastner, Renate; Wienerroither, Sebastian; Lassnig, Caroline; Putz, Eva Maria; Majer, Olivia; Reutterer, Benjamin; Sexl, Veronika; Kuchler, Karl; Müller, Mathias; Decker, Thomas; Ellmeier, Wilfried (2013). The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection. PLOS ONE;8(3):e60476. PMID: 23544144