Publications since 2006

Zaffagnini, Gabriele; Savova, Adriana; Danieli, Alberto; Romanov, Julia; Tremel, Shirley; Ebner, Michael; Peterbauer, Thomas; Sztacho, Martin; Trapannone, Riccardo; Tarafder, Abul K; Sachse, Carsten; Martens, Sascha (2018). p62 filaments capture and present ubiquitinated cargos for autophagy. EMBO J. PMID: 29343546
Fracchiolla, Dorotea; Martens, Sascha (2018). Sorting out "non-canonical" autophagy. EMBO J. PMID: 29431607
Zaffagnini, Gabriele; Savova, Adriana; Danieli, Alberto; Romanov, Julia; Tremel, Shirley; Ebner, Michael; Peterbauer, Thomas; Sztacho, Martin; Trapannone, Riccardo; Tarafder, Abul K; Sachse, Carsten; Martens, Sascha (2018). Phasing out the bad-How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy. AUTOPHAGY. PMID: 29929426
Danieli, Alberto; Martens, Sascha (2018). p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy. J CELL SCI;131(19). PMID: 30287680
Martens, Sascha (2018). A division of labor in mTORC1 signaling and autophagy. Sci Signal;11(559). PMID: 30514809
Fracchiolla, D.; Zens,B.; S. Martens (2017). In Vitro Reconstitution of Atg8 Conjugation and Deconjugation. METHOD ENZYMOL;587:377–390. PMID: 28253967
Fracchiolla, Dorotea; Sawa-Makarska, Justyna; Martens, Sascha (2017). Beyond Atg8 binding: the role of AIM/LIR motifs in autophagy. AUTOPHAGY;5(13):978-979. PMID: 28121222
Abreu, Susana; Kriegenburg, Franziska; Gómez-Sánchez, Rubén; Mari, Muriel; Sánchez-Wandelmer, Jana; Skytte Rasmussen, Mads; Soares Guimarães, Rodrigo; Zens, Bettina; Schuschnig, Martina; Hardenberg, Ralph; Peter, Matthias; Johansen, Terje; Kraft, Claudine; Martens, Sascha; Reggiori, Fulvio (2017). Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation. EMBO REP;18(5):765-780. PMID: 28330855
Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; Harper, J Wade; Jäättelä, Marja; Johansen, Terje; Juhasz, Gabor; Kimmelman, Alec C; Kraft, Claudine; Ktistakis, Nicholas T; Kumar, Sharad; Levine, Beth; Lopez-Otin, Carlos; Madeo, Frank; Martens, Sascha; Martinez, Jennifer; Melendez, Alicia; Mizushima, Noboru; Münz, Christian; Murphy, Leon O; Penninger, Josef M; Piacentini, Mauro; Reggiori, Fulvio; Rubinsztein, David C; Ryan, Kevin M; Santambrogio, Laura; Scorrano, Luca; Simon, Anna Katharina; Simon, Hans-Uwe; Simonsen, Anne; Tavernarakis, Nektarios; Tooze, Sharon A; Yoshimori, Tamotsu; Yuan, Junying; Yue, Zhenyu; Zhong, Qing; Kroemer, Guido (2017). Molecular definitions of autophagy and related processes. EMBO J;36(13):1811-1836. PMID: 28596378
Sánchez-Wandelmer, Jana; Kriegenburg, Franziska; Rohringer, Sabrina; Schuschnig, Martina; Gómez-Sánchez, Rubén; Zens, Bettina; Abreu, Susana; Hardenberg, Ralph; Hollenstein, David; Gao, Jieqiong; Ungermann, Christian; Martens, Sascha; Kraft, Claudine; Reggiori, Fulvio (2017). Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation. NAT COMMUN;8(1):295. PMID: 28821724
Zaffagnini, G.; Martens, S. (2016). Mechanisms of selective autophagy. J MOL BIOL;428:1714-24. . PMID: 26876603
Richter, Benjamin; Sliter, Danielle A; Herhaus, Lina; Stolz, Alexandra; Wang, Chunxin; Beli, Petra; Zaffagnini, Gabriele; Wild, Philipp; Martens, Sascha; Wagner, Sebastian A; Youle, Richard J; Dikic, Ivan (2016). Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. P NATL ACAD SCI USA;113(15):4039-44. PMID: 27035970
Maric-Biresev, Jelena, Hunn, Julia P., Krut, Oleg, Helms,J. Bernd, Martens, Sascha and Jonathan C. Howard (2016). Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection. BMC BIOL;14:33. PMID: 27098192
Martens, Sascha (2016). Necessary, but also Sufficient? TRENDS CELL BIOL;26(7):467-9. PMID: 27142894
Turco, E., Martens, S. (2016). Insights into autophagosome biogenesis from in vitro reconstitutions. J STRUCT BIOL. PMID: 27251905
Abert, C., Kontaxis, G., and Martens, S. (2016). Accessory Interaction Motifs in the Atg19 Cargo Receptor Enable Strong Binding to the Clustered Ubiquitin-Related Atg8 Protein. J BIOL CHEM;291:18799-18808. PMID: 27402840
Martens, S., Nakamura, S., and Yoshimori, T. (2016). Phospholipids in Autophagosome Formation and Fusion J MOL BIOL;428(24):4819–4827. PMID: 27984040
Fracchiolla, D., Sawa-Makarska, J., Zens, B., de Ruiter, A., Zaffagnini,G., Brezovich, A., Romanov, J., Runggatscher, K., Kraft,C., Zagrovic, B. and Sascha Martens (2016). Mechanism of cargo-directed Atg8 conjugation during selective autophagy eLife. PMID: 27879200
Martens, S. (2016). No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy. J CELL BIOL. PMID: 27888204
Zens, Bettina; Sawa-Makarska, Justyna; Martens, Sascha (2015). In vitro systems for Atg8 lipidation. METHODS;75:37-43. PMID: 25461810