Kazufumi Mochizuki & his group moved to IGH Montpellier in 2016.
Full member of the DoktoratsKolleg RNA Biology since 2007 until 2016
DK RNA Alumni:
Sophie Soyka: “Characterization of a novel gene from Tetrahymena thermophila involved in RNA directed DNA elimination”
Jan Henrik Suhren: “Small RNA-directd heterochromatin formtion in Tetrahymena thermophila”
Ursula Schöberl: “RNA-directed DNA elimination in Tetrahymena thermophila”
Transgenerational epigenetic inheritance has been observed in a wide variety of eukaryotes from plants to mammals while its molecular mechanism is still unclear. Our group studies such an epigenetic inheritance process that regulates programmed DNA elimination in the ciliated protozoan Tetrahymena. Nuclear-acting small RNAs mediate the communication between the parental and gremlin genomes and we try to understand how these small RNAs are utilized to establish the epigenetic inheritance.