Biochemistry & Biophysics | Immunology & Pathogens

Early interactions of viruses with host cells

Dieter Blaas
Group Leader

dieter.blaas [AT] [DOT] at
Phone: +43-1-4277-61630
Dr. Bohr-Gasse 9, 1030 Vienna | Room: 3.026

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To infect a host cell, viruses usually recognize particular structures on the cell surface. Following binding to these ‘viral receptors’, the virons are taken up into the cell along different entry routes. Most of these pathways converge in vesicular structures, the endosomes. Depending on whether the virus is covered with a lipid membrane (enveloped) or lacking such a membrane (naked), its genome is then being released into the cytoplasm by different mechanisms. Enveloped




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