Molecular Cell Biology | Neuroscience

The neuronal cytoskeleton in axon guidance

Friedrich Propst
Group Leader

friedrich.propst [AT] [DOT] at
Phone: +43-1-4277-52858
Dr. Bohr-Gasse 9, 1030 Vienna | Room: 5.528/5.530

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Axon extension, branching, and retraction are morphological changes that neurons have to execute to accomplish correct wiring of the nervous system during development and regeneration. These transformations are guided by extracellular signals which ultimately need to be translated into rearrangement of the neuronal cytoskeleton. We study mechanisms involved in the orchestrated reorganization of neuronal microtubules and actin filaments. Our approach combines gene ablation in



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