Publications since 2006

Temmel, Hannes; Müller, Christian; Sauert, Martina; Vesper, Oliver; Reiss, Ariela; Popow, Johannes; Martinez, Javier; Moll, Isabella (2017). The RNA ligase RtcB reverses MazF-induced ribosome heterogeneity in Escherichia coli. NUCLEIC ACIDS RES;8(45):4708-4721. PMID: 27789694
Martinez, Javier; Zagrovic, Bojan (2016). A code within a code: how codons influence mRNA stability. EMBO J;35(17):1845 - 1955. PMID: 27562506
Weitzer, Stefan; Hanada, Toshikatsu; Penninger, Josef M; Martinez, Javier (2015). CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders. Wiley Interdiscip Rev RNA;6(1):47-63. PMID: 25142875
Jurkin, Jennifer; Henkel, Theresa; Nielsen, Anne Færch; Minnich, Martina; Popow, Johannes; Kaufmann, Therese; Heindl, Katrin; Hoffmann, Thomas; Busslinger, Meinrad; Martinez, Javier (2014). The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO J;33(24):2922-36. PMID: 25378478
Karaca, Ender; Weitzer, Stefan; Pehlivan, Davut; Shiraishi, Hiroshi; Gogakos, Tasos; Hanada, Toshikatsu; Jhangiani, Shalini N; Wiszniewski, Wojciech; Withers, Marjorie; Campbell, Ian M; Erdin, Serkan; Isikay, Sedat; Franco, Luis M; Gonzaga-Jauregui, Claudia; Gambin, Tomasz; Gelowani, Violet; Hunter, Jill V; Yesil, Gozde; Koparir, Erkan; Yilmaz, Sarenur; Brown, Miguel; Briskin, Daniel; Hafner, Markus; Morozov, Pavel; Farazi, Thalia A; Bernreuther, Christian; Glatzel, Markus; Trattnig, Siegfried; Friske, Joachim; Kronnerwetter, Claudia; Bainbridge, Matthew N; Gezdirici, Alper; Seven, Mehmet; Muzny, Donna M; Boerwinkle, Eric; Ozen, Mustafa; Clausen, Tim; Tuschl, Thomas; Yuksel, Adnan; Hess, Andreas; Gibbs, Richard A; Martinez, Javier; Penninger, Josef M; Lupski, James R (2014). Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. CELL;157(3):636-50. PMID: 24766809
Popow, Johannes; Jurkin, Jennifer; Schleiffer, Alexander; Martinez, Javier (2014). Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. NATURE;511(7507):104-7. PMID: 24870230
Gebeshuber, Christoph A; Kornauth, Christoph; Dong, Lihua; Sierig, Ralph; Seibler, Jost; Reiss, Martina; Tauber, Stefanie; Bilban, Martin; Wang, Shijun; Kain, Renate; Böhmig, Georg A; Moeller, Marcus J; Gröne, Hermann-Josef; Englert, Christoph; Martinez, Javier; Kerjaschki, Dontscho (2013). Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1. Nature medicine.;19(4):481-7. PMID: 23502960
Mair, Barbara; Popow, Johannes; Mechtler, Karl; Weitzer, Stefan; Martinez, Javier (2013). Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components. BIOCHEM SOC T;41(4):831-7. PMID: 23863140
Gebeshuber, C A; Martinez, J (2013). miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. ONCOGENE;32(27):3306-10. PMID: 22926517
Hanada, Toshikatsu; Weitzer, Stefan; Mair, Barbara; Bernreuther, Christian; Wainger, Brian J; Ichida, Justin; Hanada, Reiko; Orthofer, Michael; Cronin, Shane J; Komnenovic, Vukoslav; Minis, Adi; Sato, Fuminori; Mimata, Hiromitsu; Yoshimura, Akihiko; Tamir, Ido; Rainer, Johannes; Kofler, Reinhard; Yaron, Avraham; Eggan, Kevin C; Woolf, Clifford J; Glatzel, Markus; Herbst, Ruth; Martinez, Javier; Penninger, Josef M (2013). CLP1 links tRNA metabolism to progressive motor-neuron loss. NATURE;495(7442):474-80. PMID: 23474986
Popow, Johannes; Schleiffer, Alexander; Martinez, Javier (2012). Diversity and roles of (t)RNA ligases. CELL MOL LIFE SCI;69(16):2657-70. PMID: 22426497
Popow, Johannes; Englert, Markus; Weitzer, Stefan; Schleiffer, Alexander; Mierzwa, Beata; Mechtler, Karl; Trowitzsch, Simon; Will, Cindy L; Lührmann, Reinhard; Söll, Dieter; Martinez, Javier (2011). HSPC117 is the essential subunit of a human tRNA splicing ligase complex. SCIENCE;331(6018):760-4. PMID: 21311021