Publications since 2006

Kovarik, Pavel; Ebner, Florian; Sedlyarov, Vitaly (2017). Posttranscriptional regulation of cytokine expression. Cytokine.;89:21-26. PMID: 26586165
Lang, Michaela; Berry, David; Passecker, Katharina; Mesteri, Ildiko; Bhuju, Sabin; Ebner, Florian; Sedlyarov, Vitaly; Evstatiev, Rayko; Dammann, Kyle; Loy, Alexander; Kuzyk, Orest; Kovarik, Pavel; Khare, Vineeta; Beibel, Martin; Roma, Guglielmo; Meisner-Kober, Nicole; Gasche, Christoph (2017). HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis. CANCER RES;9(77). PMID: 28428272
Ebner F, Sedlyarov V, Tasciyan S, Ivin M, Kratochvill F, Gratz N, Kenner L, Villunger A, Sixt M, Kovarik P (2017). The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. J CLIN INVEST;6(127):2051-2065. PMID: 28504646
Masa Ivin, Amy Dumigan, Filipe N. de Vasconcelos, Florian Ebner, Martina Borroni, Anoop Kavirayani, Kornelia N. Przybyszewska, Rebecca J. Ingram, Stefan Lienenklaus, Ulrich Kalinke, Dagmar Stoiber, Jose A. Bengoechea, Pavel Kovarik (2017). Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection PLOS PATHOG.
Fallmann, Jörg; Sedlyarov, Vitaly; Tanzer, Andrea; Kovarik, Pavel; Hofacker, Ivo L (2016). AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements. NUCLEIC ACIDS RES;4(44):D90-5. PMID: 26602692
Castiglia, Virginia; Piersigilli, Alessandra; Ebner, Florian; Janos, Marton; Goldmann, Oliver; Damböck, Ursula; Kröger, Andrea; Weiss, Sigfried; Knapp, Sylvia; Jamieson, Amanda M; Kirschning, Carsten; Kalinke, Ulrich; Strobl, Birgit; Müller, Mathias; Stoiber, Dagmar; Lienenklaus, Stefan; Kovarik, Pavel (2016). Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. Cell Host Microbe;19(3):375-87. PMID: 26962946
Sedlyarov, Vitaly; Fallmann, Jörg; Ebner, Florian; Huemer, Jakob; Sneezum, Lucy; Ivin, Masa; Kreiner, Kristina; Tanzer, Andrea; Vogl, Claus; Hofacker, Ivo; Kovarik, Pavel (2016). Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution. MOL SYST BIOL;12(5):868. PMID: 27178967
Gamradt, Pia; Xu, Yun; Gratz, Nina; Duncan, Kellyanne; Kobzik, Lester; Högler, Sandra; Kovarik, Pavel; Decker, Thomas; Jamieson, Amanda M (2016). The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes. PLOS PATHOG;12(12):e1006032. PMID: 27973535
Kovarik, Pavel; Castiglia, Virginia; Ivin, Masa; Ebner, Florian (2016). Type I Interferons in Bacterial Infections: A Balancing Act. Frontiers in immunology;7:652. PMID: 28082986
Wiesauer, Ivana; Gaumannmüller, Clemens; Steinparzer, Iris; Strobl, Birgit; Kovarik, Pavel (2015). Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription. MOL CELL BIOL;35(4):716-27.. PMID: 25512607
Fieber, Christina; Janos, Marton; Koestler, Tina; Gratz, Nina; Li, Xiao-Dong; Castiglia, Virginia; Aberle, Marion; Sauert, Martina; Wegner, Mareike; Alexopoulou, Lena; Kirschning, Carsten J; Chen, Zhijian J; von Haeseler, Arndt; Kovarik, Pavel (2015). Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2. PLOS ONE;10(3):e0119727. PMID: 25756897
Kratochvill, Franz; Gratz, Nina; Qualls, Joseph E; Van De Velde, Lee-Ann; Chi, Hongbo; Kovarik, Pavel; Murray, Peter J (2015). Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. CANCER RES;75(15):3054-64. PMID: 26183929
Dinis, Márcia; Plainvert, Céline; Kovarik, Pavel; Longo, Magalie; Fouet, Agnès; Poyart, Claire (2014). The Innate Immune Response Elicited by Group A Streptococcus Is Highly Variable among Clinical Isolates and Correlates with the emm Type. PLOS ONE;9(7):e101464. PMID: 24991887
Fieber, Christina; Kovarik, Pavel (2014). Responses of innate immune cells to group A Streptococcus. Frontiers in cellular and infection microbiology;4:140. PMID: 25325020
Kovarik, Pavel; Castiglia, Virginia; Janos, Marton (2014). Type I Interferons in Immune Defense Against Streptococci. Bacterial Activation of Type I Interferons:43-59.
Bancerek, Joanna; Poss, Zachary C; Steinparzer, Iris; Sedlyarov, Vitaly; Pfaffenwimmer, Thaddäus; Mikulic, Ivana; Dölken, Lars; Strobl, Birgit; Müller, Mathias; Taatjes, Dylan J; Kovarik, Pavel (2013). CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response. IMMUNITY:250-62. PMID: 23352233
Gruber AR; Fallmann J; Kratochvill F; Kovarik P; Hofacker I. (2011). AREsite: a database for the comprehensive investigation of AU-rich elements NUCLEIC ACIDS RES. PMID: 21071424
Roetzer A; Klopf E; Gratz N; Marcet-Houben M; Hiller E; Rupp S; Gabaldón T; Kovarik P; Schüller C. (2011). Regulation of Candida glabrata oxidative stress resistance is adapted to host environment. FEBS Lett;585(2):319-27. PMID: 21156173
Gratz, Nina; Hartweger, Harald; Matt, Ulrich; Kratochvill, Franz; Janos, Marton; Sigel, Stefanie; Drobits, Barbara; Li, Xiao-Dong; Knapp, Sylvia; Kovarik, Pavel (2011). Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLOS PATHOG;7(5):e1001345. PMID: 21625574
Kratochvill, Franz; Machacek, Christian; Vogl, Claus; Ebner, Florian; Sedlyarov, Vitaly; Gruber, Andreas R; Hartweger, Harald; Vielnascher, Raimund; Karaghiosoff, Marina; Rülicke, Thomas; Müller, Mathias; Hofacker, Ivo; Lang, Roland; Kovarik, Pavel (2011). Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. MOL SYST BIOL;7:560. PMID: 22186734