Laura Gallego Valle is Researcher of the Month November at the Medical University of Vienna

03/11/2017

Congratulations to Laura, PhD student in Alwin Köhler’s lab! She is awarded on occasion of her recent publication “Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1”. This paper is the result of a multidisciplinary study carried out between the MFPL and the IMP in Vienna, and groups in LMU (Munich, Germany) and HHMI - University of Washington (Seattle, USA). 

Laura is interested in epigenetics, specifically, on how the modification of chromatin with the small protein ubiquitin regulates transcription. This is a fundamental process both in healthy cells and in deranged form in human cancers. Over the past years, the Köhler lab has made important contributions to the field of chromatin ubiquitination, most recently by showing how the ubiquitin system can recognize chromatin with high specificity – the publication Laura is awarded for. Laura has already won the L’Oreal Austria Fellowship this year, and was previously awarded a DOC fellowship of the Austrian Academy of Sciences.

More info about the Researcher of the Month can be found here.

Publication:
Gallego L.D., Ghodgaonkar Steger M, Polyansky A, Schubert T, Zagrovic B, Zheng N, Clausen T, Herzog F, and Köhler A; Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1. PNAS (2016) 113(38):10553-10558